Introduction

Penile Cancer (PC) is uncommon in Western countries. Due to its low incidence and low volume of surgical series it is difficult to achieve good quality guidelines with robust recommendations. Aims of this study were 1) to evaluate the adherence to the EAU guidelines on PC in terms of primary treatment and lymphadenectomy; 2) to weight the impact of the adherence on survival outcomes._x000D_ _x000D_ _x000D_

Methods

We retrospectively reviewed the clinical charts of 176 patients underwent penile surgery for cancer in 8 European Centres. Demographics, circumcision, site of primary lesion, perioperative and histopathological data were collected and analysed. The follow-up was updated by recall of all patients._x000D_ A comparison between theoretical and practical surgical and lymphoadenectomy approach was done in order to evaluate the adherence rate. Descriptive, univariate and multivariate analyses were performed to evaluate the impact of the adherence on survival with Kaplan-Meier curves._x000D_ _x000D_ _x000D_

Results

176 patients were enrolled (median age 66.5 y +/- 11.3). The lesions were located at the glans, the prepuce and on both sites in 55%, 11% and 34%, respectively. The surgical approaches adopted were radical circumcision, tumor excision, glansectomy, penile partial amputation, total emasculation in 7%, 24%, 15%, 39%, 15%, respectively.The staging was 16%

Conclusions

Our data showed that the adherence to the EAU Guidelines on PC strongly influences the survival outcomes._x000D_ _x000D_

Funding

none