Abstract: PD48-02
Sources of Funding: None

Introduction

This study aimed to evaluate the immediate second resection of tumor bed after complete transurethral resection (TUR) could improve the quality of the initial TUR.

Methods

We retrospectively collected the data from 304 patients (immediate second resection group; ISR group) who had underwent immediate second resection as previously reported (Kim et al. J Endourol 2008) and 232 patients (non-second resection group; NSR group) who had not undergone immediate second resection by other surgeon. Confounding variables including age, gender, multiplicity of tumor, tumor size, pathologic tumor stage, pathologic tumor grade were matched in the two study groups using propensity score matching.

Results

The propensity score matched model included 6 variables, and matching by propensity score yielded 170 patients in ISR group matched to 170 patients in NSR group. (ISR group; 97 Ta, 6 CIS and 67 T1, NSR group; 94 Ta, 7 CIS and 69 T1). Of the patients who received restaging TUR (ISR group; 46 vs. NSR group; 39), the absence of residual tumors was significantly greater in ISR group than NSR group (74.3% vs. 47.8%, p=0.002). Among the patients with non-muscle invasive bladder tumor, ISR group demonstrated significantly better outcomes compared to NSR group in terms of 2-year RFS (82.9% vs.66.1%, p<0.001). The patient with high risk disease showed that the 2-year RFS was better for those who underwent immediate second resection than those who did not (83.7% vs. 56.6. p<0.001).

Conclusions

After controlling for variables affecting disease recurrence, the immediate second resection of tumor bed after complete TUR of bladder tumor improved recurrence free survival in patients with non-muscle invasive bladder tumor._x000D_ _x000D_

Funding

None