Abstract: PD39-09
Sources of Funding: None

Introduction

Detrusor underactivity is an important yet still under-research issue. The treatment outcome in patients with detrusor underactivity (DU) is usually unfavorable and no better compared to untreated patients. Therefore, we aim to identify the predictive factors of satisfactory treatment in male patients with detrusor underactivity.

Methods

We retrospectively reviewed 86 cases of men with video-urodynamic proven detrusor underactivity from 2000 to 2015. DU was defined as low voiding pressure, low flow rate, post void residual (PVR)>300mL and a low voiding efficiency (VE) < 33% in this study. VE > 50% after treatment was considered satisfactory outcome. Patient’s demographics and urodynamic parameters include first sensation of filling (FSF), full sensation of filling (FS), urgency sensation (US), compliance at capacity, maximal flow rate (Qmax), detrusor voiding pressure (Pdet), voided volume, cystometric bladder capacity (CBC) and PVR were compared between the satisfactory group and unsatisfactory group. Various treatment options including transurethral resection of prostate (TURP), transurethral incision of prostate (TUIP) and medication (include botulinum toxin injection) were performed according to clinical and video-urodynamics findings.

Results

After a mean follow up of 31 months, 63 patients had satisfactory outcome. Satisfactory group has significantly higher detrusor pressure and compliance at capacity than unsatisfactory group. There was significant improvement in FSF, FD, US, Pdet, Qmax, voided volume, PVR and CBC after treatment in satisfactory group meanwhile in unsatisfactory group there were only significant changes in US, PVR and CBC.

Conclusions

A higher detrusor pressure and compliance at capacity at baseline were predictive of satisfactory treatment outcomes in male patient with detrusor underactivity.

Funding

None