Abstract: PD38-05
Sources of Funding: None

Introduction

To investigate the prevalence of urinary retention in male bladder cancer patients who underwent radical cystectomy and orthotopic neobladder (NB) and to identify potential predictors of retention, if any.

Methods

Using an IRB approved, prospectively maintained database, we identified 265 males who underwent radical cystectomy with NB at our institution from 3/2000 to 6/2015 and completed post operative questionnaires regarding catheterization. The mean age at surgery was 65.7 years and mean BMI was 27.42. Univariate logistic analysis was performed for potential predictors of catheterization and urinary retention. Retention was defined as 3 or more catheterizations per day or self-reported inability to void without catheterizing.

Results

The need to catheterize at all was noted in 33 of 265 (12.4%) patients. Of these, 11 (4.2% of the total) were determined to be in retention or required catheterization to void. Data regarding the number of catheterizations per day was available in 32 of these patients (Table 1). Univariate analysis showed that increasing BMI significantly predicted the need for catheterization (p = 0.009, coefficient = 0.097). Diabetes and moderate-to-severe renal disease approached significance (p-value = 0.075 and 0.09, respectively), but there were otherwise no significant predictors of the need to catheterize. Additionally, no significant predictors of urinary retention were found (Table 2).

Conclusions

In males undergoing radical cystectomy with NB, retention requiring catheterization to void is uncommon. In this large cohort, the rate of any catheterization at all was 12.4%, of which a small fraction (4.2%) had complete urinary retention. BMI was found to significantly correlate with the need to catheterize, but age, medical comorbidities, pathologic stage, and receiving neoadjuvant chemotherapy did not have significant correlations with urinary retention. Larger power studies are required to further evaluate these predictors.

Funding

None