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Complications of Holmium Laser Enucleation of the Prostate: A Single Centre Case Series with 13 years of follow-up

Abstract: PD27-05
Sources of Funding: None

Introduction

Holmium laser enucleation of the prostate (HoLEP) is an established effective alternative treatment option to the traditional transurethral resection of the prostate for bladder outflow obstruction secondary to benign prostatic hyperplasia. As a relatively new procedure long-term outcomes for patients undergoing HoLEP are still being studied. We describe the complications of a large single centre case series with up to 13 years of post-operative follow-up.

Methods

A retrospective review of a prospective database of all HoLEP procedures performed by or under supervision of a single consultant urological surgeon was undertaken. All case notes were reviewed for complications up to October 2016 and recorded in accordance with the Clavien-Dindo classification system. Statistical analysis was performed using a Mann-Whitney U test.

Results

969 cases of HoLEP were performed at our centre between December 2003 and October 2016. There was a statistically significant improvement in both urinary flow rate and post-void residual volumes (p<0.0001). Median pre-operative flow rate was 8.4ml/s (range 1-26.3) (n=536) and post-operative flow rate was 19.5ml/s (range 1.8-68.4) (n=649). Median pre-operative post-void residual volumes were 263mls (range 0-5000) (n=718) and post-operative residual volumes were 71mls (0-1000)._x000D_ 188 patients (23.6%) were discharged from hospital on the day of surgery; 479 (60.1%) on day 1; 85 (10.7%) on day 2; 45 (5.6%) stayed 3 days or more (n=797)._x000D_ Post-operative early and late complications are recorded within the table._x000D_

Conclusions

HoLEP is an effective and safe treatment for bladder outflow obstruction associated with few early and late complications.

Funding

None

Authors
Danielle Whiting
Thomas Smith
Branimir Penev
Mark Cynk
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