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Medium Term Outcomes of Ventral -Onlay Buccal Mucosa Graft Substitution Urethroplasty for Urethral Stricture in Females

Abstract: PD26-04
Sources of Funding: None

Introduction

Female urethral stricture causes significant morbidity. There is a high rate of recurrence following endoscopic management. Urethroplasty for female urethral stricture (FUS) is a rare but increasingly common procedure. We report our medium term outcomes for ventral-onlay buccal mucosa graft substitution urethroplasty (VOBMGSU) in treating FUS.

Methods

From our prospectively acquired database we reviewed the outcomes of 22 consecutive women (median age 50 years, range 34-72) with FUS having VOBMGSU from June 2012 and with a minimum follow up of 6 months (median 21.5, range 6-51). Data was analysed for complications, stricture recurrence, change in median peak free flow rate (Qmax) and median post-void residuals (PVR). Statistical analysis was performed using the Wilcoxon signed rank test, Students TTest and Mann-Whitney U Test .

Results

At last follow-up 21/22 (95%) of women were stricture free. Median Qmax was significantly improved from 7 ml/s (range 3.5-11.2) to 18 ml/s (range 5- 37) (p < 0.05). Median PVR was significantly reduced from 100mls (range 0-300) to 15 mls (range 0-150) (p < 0.05). Short and longer-term complication rates were low. 1 patient developed mild de novo stress urinary incontinence, which settled with conservative measures by 6 months.

Conclusions

Early and medium term results indicate that VOBMGSU is an excellent treatment for female urethral stricture that can avoid the need for the repeat procedures regularly required after traditional endoscopic management.

Funding

None

Authors
Bashir Mukhtar
Marco Spilotros
Mahreen Pakzad
Rizwan Hamid
Jeremy Ockrim
Tamsin Greenwell
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