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Factors associated with early recovery of stress urinary incontinence following Holmium laser enucleation of prostate in patients with benign prostatic hyperplasia

Abstract: PD23-09
Sources of Funding: none

Introduction

We investigated factors associated with early recovery of stress urinary incontinence (SUI) following holmium laser enucleation of prostate (HoLEP) in patients with BPH.

Methods

We retrospectively reviewed the medical records of 393 patients who had undergone HoLEP for BPH. Those with prostate cancer diagnosed before or after HoLEP, a history of other prostatic and/or urethral surgery, moderate to severe postoperative complications, and neurogenic causes were excluded. Patients with SUI following HoLEP were included, and we divided the patients into two groups: the early recovery of SUI group and the persistent SUI group. Early recovery of SUI was defined as recovery of SUI within one month after HoLEP, and persistent SUI was defined as SUI is still present after one month. Preoperative clinical and urodynamic factors, as well as perioperative factors, were compared between groups.

Results

SUI following HoLEP was found in 86 patients (86/393, 21.9%). Thirty-three patients (33/86, 38.4%) showed recovery of SUI within one month, and SUI was still present in 53 patients (53/86, 61.6%) after one month. The preoperative clinical characteristics and urodynamic parameters are shown in Table 1. The transitional zone volume of prostate in the early recovery of SUI group was higher than that in the persistent SUI group. In a comparison of perioperative factors, enucleation ratio (enucleation weight/transitional zone volume) in the early recovery of SUI group was lower than that in the persistent SUI group. (0.65 ± 0.32 vs 0.9 ± 0.69, P = 0.010) A multivariate analysis showed that the enucleation ratio (OR 4.252, 95%CI 1.112-16.261, P = 0.034) was significantly associated with the early recovery of SUI.

Conclusions

Persistent SUI for more than one month following HoLEP occurred in some patients, and the high enucleation ratio could be associated with it. These patients would need early management for SUI following HoLEP.

Funding

none

Authors
Kang Jun Cho
Jun Sung Koh
Hyun Woo Kim
Dong Hwan Lee
Hyo Sin Kim
Joon Chul Kim
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