Advertisement

Is endoscopic evaluation at the end of retrograde intra-renal surgery a reliable predictor of post-operative significant residual fragments?

Abstract: PD21-08
Sources of Funding: None

Introduction

Post-operative imaging used to assess retrograde intra-renal surgery (RIRS) results affects stone-free rates (SFR). Imaging after RIRS may be unnecessary if surgeon&[prime]s endoscopic evaluation (EE) at the end of RIRS proved to be reliable._x000D_ The objective of our study was to assess the reliability of surgeon&[prime]s EE at the end of RIRS.

Methods

We made a retrospective analysis on all consecutive RIRS performed for renal stones from January 2009 to August 2016 and included in a prospectively maintained database. RIRS were performed with fiber optics instruments in one-day surgery under spinal anesthesia. A ureteral access sheath was used, laser lithotripsy was performed and significant fragments extracted. Multiple stones, stones > 2 cm and staged procedures were included. Surgeons recorded their EE particularly about the presence of significant residual fragments (SRF). Residual fragments were considered clinically insignificant (CIRF) if ≤ 4 mm. Primary endpoint of our study was the ability of EE made by an expert surgeon to exclude the presence of SRF at US at 2-3 weeks. Chi-square and Fisher tests were used for statistical analysis.

Results

294 RIRS were included. EE was available in 281 cases and US in 211. Mean stone size was 12.31 mm ± 4.87 mm (SD). In 68 cases (23.13%) stones were multiple. Post-operative US outcomes significantly differed from urologist&[prime]s EE in term of SRF, CIRF and SFR (p < 0.0001), independently from the number of RIRS performed per year by the surgeon (p < 0.001). 14% more patients were found stone-free (SFR 0U) at US compared to EE, 28% less were found to have CIRF and 14% more to have SRF. Table 1 shows how the concordance of EE and US outcomes varied in relation with surgeon&[prime]s expertise. In particular the difference in terms of SRF and CIRF decreased when EE was made by a surgeon performing ≥ 20 RIRS/year. The absence of SRF assessed at EE by a surgeon performing ≥ 20 RIRS/year was confirmed at US in 92% of cases. The probability to diagnose at US SRF not assessed at EE increased to 36% when EE was made by surgeons performing < 20 RIRS/year (OR = 6.4).

Conclusions

Post-operative US outcomes significantly differed from urologist&[prime]s EE. EE underestimated SFR and overestimated CIRF. SRF were underestimated at EE, but an expert surgeon reliably predicted the absence of SRF.

Funding

None

Authors
Andrea Bosio
Eugenio Alessandria
Ettore Dalmasso
Dario Peretti
Federico Vitiello
Alessandro Bisconti
Paolo Destefanis
Paolo Gontero
back to top