Predictors of Membranous Urethral Length Measurement Prior to Radical Prostatectomy
Sources of Funding: None
Introduction
Patient anatomical factors including the preoperative measurement of the membranous urethral length (MUL) have been reported to affect the time to achieve continence following radical prostatectomy (RP). There is limited data available reporting the relationship between patient anthropometric measures and also the test-retest reliability of MUL measurements from separate MRI investigations. _x000D_ Objectives: We sought to investigate i) if patient related anthropometric factors were associated with MUL measurements in men prior to RP and ii) the test-retest reliability of preoperative MUL measurements from separate MRI investigations. _x000D_
Methods
119 preoperative T2 weighted sagittal prostate MRI‘s were cross-referenced with coronal images for the measurement of MUL. Preoperative MUL was measured three times and the mean of the three measures was recorded for analysis. A linear model was used for the regression of MUL against predictive variables height, body mass, BMI and age. Nine patients who had undergone two separate preoperative prostate MRI investigations were identified to assess the test-retest reliability of MUL measurements. An intra class correlation coefficient (ICC) using a two-way mixed-model was used to assess the reliability of the test-retest preoperative MUL measurements.
Results
The 119 patients had a mean age of age 65 8yrs, mean height 1.72 0.07m, mean body mass 84 12.8kg and a mean BMI 27.8 4.6 kg.m2. MUL was not associated with height (p=0.713), body mass (p=0.894), BMI (p=0.985) or age (p=0.189). For the 9 patients with two separate prostate MRI investigations, there was excellent test-retest reliability for the preoperative measurement of MUL ICC=0.989 (95%CI: 0.935, 0.998). The average time between MRI investigations was 35 64 days.
Conclusions
Patient anthropometric measurements are not related to MUL in men prior to RP. The two repeated measurements of MUL from separate MRI investigations indicates that MUL is a stable measurement, but due to the small sample size further investigation is warranted.
Funding
None
Petra Graham
Jaspreet Sandhu
Oguz Akin
Manish Patel