Login to Access Video or Poster Abstract: MP90-05
Sources of Funding: None

Introduction

The most common lifestyle preventative treatment of stone disease is increasing fluid intake. However, many patients experience lower urinary tract symptoms (LUTS) that may impair their ability to increase fluid intake. The objective of this study is to determine if there is a correlation between International Prostate Symptom Scores (IPSS) and 24-hour urine collection volumes.

Methods

We retrospectively reviewed all kidney stone patients over a 2 year period who were given IPSS questionnaires at the time of their initial consultation, and their subsequent 24-hr urine collections. Exclusion criteria included symptomatic stone or urinary tract infection at time of IPSS completion, inadequate 24-hour collection, or incomplete IPSS questionnaire.

Results

Overall, 131 patients met inclusion criteria, with a mean age of 53 years. Stratification by IPSS score into mild (0-7), moderate (8-19), and severe (20-35) yielded groups of N=96, 28, and 7, respectively. Linear regression modelling did not reveal a correlation between IPSS score and volume (p=0.1). There was no difference between urine volumes in the mild, moderate and severe groups (p=0.07). However, when comparing those with severe LUTS to the rest of the population, they showed significantly lower daily urine volumes (mean 1.4 L/day vs 2.0 L/day; p=0.02). _x000D_ _x000D_ When patients with low urine outputs (≤1 L/day) (N=1F:9M, mean age 54 years old), were compared to those adequate urine volumes (≥2 L/day) (N=6F:59M, mean age 52 years old), a significantly higher overall IPSS score was noted (11.7 vs. 6.1; p=0.04). Low output patients reported significantly higher scores on the questions related to incomplete emptying (1.8 vs. 0.7; p=0.03), intermittency (1.7 vs. 0.6; p=0.01), and straining (1.8 vs. 0.4; p=0.002)._x000D_

Conclusions

This study is the first to examine the correlation between IPSS score and 24-hour urine volume. Though our data does not show a linear relationship between urine output and IPSS; those with lower urine volumes (≤1 L/day) have significantly worse self reported voiding symptoms when compared to those with adequate volumes (≥2 L/day) for stone prevention.

Funding

None