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A novel use of structured water for the prevention of recurrent stones in idiopathic hypercalciuria.

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Sources of Funding: none

Introduction

The majority of stones (85%) contain primarily calcium oxalate. Most renal stones are idiopathic calcium stones, and the most common predisposing factor in these patients is hypercalciuria. Structured water is a new type of water that has been prepared using different types of energy fields and modulators to produce this structured water that has new and different characteristics from the ordinary water. _x000D_ In this study, we compared the efficacy of the structured water (Magnalife®) with hydrochlorothiazide and with ordinary bottled water in the prevention of recurrent renal stones in patients with idiopathic hypercalciuria._x000D_

Methods

We conducted a three-year randomized trial comparing the effect of structured water with the effect of hydrochlorothiazide and ordinary bottled water in 300 patients with recurrent calcium oxalate stones and hypercalciuria. 100 men used structured water (Magnalife®). The other 100 men used 50 mg hydrochlorothiazide, and 100 men used ordinary bottled water._x000D_ Urine analysis with renal ultrasonography and radiology were done at baseline and at yearly intervals and any time of recurrence and at the end of the 3 years (36th month). All patients were informed and signed a written informed consent form._x000D_

Results

Of the 300 men included in this study, 95 had recurrent stones, 15 men (15%) in the group of structured water ,31 men (31%) in the hydrochlorothiazide group, and 49 men (49%) in the group of ordinary bottled water. The difference in the recurrence rate between the structured water group and the hydrochlorothiazide group is significant (P=0.007) Also the difference between the difference between the structured water group and the ordinary water group is significant (P<0.001), furthermore the hydrochlorothiazide group and the ordinary bottled water group recurrence rate is significantly different (P=0.009).

Conclusions

Structured water is a safe, effective, and affordable new way to prevent recurrent urinary stones without the need for medications that are expensive and have many side effects. Furthermore, it is more potent than some preventive measures and drugs as a prophylactic way against recurrent urinary stones. It is far more effective than ordinary bottled water in preventing recurrent stones. Further studies are recommended to explore its role in other fields of urology._x000D_

Funding

none

Authors
Ali Sami
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