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Impact of metabolic syndrome on the occurrence of premature ejaculation

Login to Access Video or Poster Abstract: MP84-08
Sources of Funding: none

Introduction

Despite the association between erectile dysfunction and metabolic syndrome (MetS), few reports describe the relationship between premature ejaculation (PE) and MetS. This study investigated the effect of MetS in the pathogenesis of ejaculatory symptoms, and the risk factors associated with PE.

Methods

Records of 1,029 men who visited our clinic for male health screening between January 2010 and July 2014 were analyzed. Multivariate analyses included the covariates of age, International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF) score, National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) score, body mass index, Androgen Deficiency in the Aging Male (ADAM) score, serum testosterone levels, and all components of MetS. PE was defined as self-reported intravaginal ejaculation latency time (IELT) <1 minute, and MetS was diagnosed by using the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. The Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EjD) was used to analyze ejaculation anxiety and other dysfunctions.

Results

Of 1,029 men, 74 (7.2%) had PE (ejaculation within 1 min) and 111 (10.8%) had MetS. Multivariate logistic regression analysis showed that IIEF overall satisfaction score, NIH-CPSI pain score, NIH-CPSI voiding score, and presence of MetS were significantly correlated with prevalence of PE. MSHQ-EjD and ejaculation anxiety scores progressively decreased as the number of components of MetS increased.

Conclusions

MetS may be an important factor predisposing to development of PE; effective prevention and treatment of MetS could also be important for the prevention of PE.

Funding

none

Authors
Seong Uk Jeh
See Min Choi
Sin Woo Lee
sol Yoon
Jae Seog Hyun
Deok Ha Seo
Chunwoo Lee
Sung Chul Kam
Ky Hyun Chung
Jeong Seok Hwa
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