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Sources of Funding: none

Introduction

Vacuum therapy allows to prevent fibrosis in the corpus cavernosum and penile length loss. But participation of VED in penile rehabilitation (PR) to prevent hypoxia of cavernosal tissue is not completely clear due to lack of data about blood gas (BG) at the time of using VED without constriction ring._x000D_ We assessed some BG analytical parameters at the time of artificial erection induced by VED and then compared it with the results of color-Doppler ultrasonography (CDU) and scores of domain EF of International Index of Erectile Function-15 (IIEF-15).

Methods

We took corporal blood after VED use from 15 patients before doing nerve-sparing radical prostatectomy (NSRP). We used acid-base parameters of venous and arterial blood of the patient for control. We measured the partial pressure of oxygen (pO2), the partial pressure of carbon dioxide (pCO2) and oxygen saturation (SO2) to determine BG and blood oxygenation. All patients who underwent preoperative comprehensive evaluation of EF with using IIEF questionnaire and CDU.

Results

15 patients were divided into three groups based on BG corporal blood after using VED: 4 with a predominance of arterial blood (26.6%), 4 with a predominance of venous blood (26.6%) and 7 with mixed blood (46,6%) respectively. Mean IIEF score and averages of pO2 (mmHg), pCO2 (mmHg) and sO2 (%) obtained during the study are shown in Table._x000D_ IIEF score and values of CDU in patients with a predominance of arterial blood in corpus cavernosum after using VED differed with higher rates comparing patients with venous and mixed blood. According acid-base parameters in the II and III groups corporal blood consists venous and mixed blood after VED therapy, where SO2 is 86.3% and 93.9%, respectively, which corresponds to the high level of oxygenation.

Conclusions

High level of oxygenation in all investigated groups is an important factor of prevention collagen synthesis and fibrosis and thereby VED can be used in PR in patients who underwent NSPR. Use of expanded opportunities of CDU is very important because it shows real penile length loss. Besides, measurement of RI shows in arterial blood group patients that the high RI (>0.8) indicates sufficient veno-occlusive mechanism. It can be used as a predictor in appointment of VED therapy for PR.

Funding

none