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The effect of ultrasound-guided compression performed immediately after transrectal ultrasound-guided prostate biopsy on postbiopsy bleeding

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Sources of Funding: none

Introduction

The effect of ultrasound-guided compression performed immediately after transrectal ultrasound-guided prostate biopsy on postbiopsy bleeding: a randomized controlled pilot study

Methods

We prospectively evaluated a total of 148 consecutive patients who underwent TRUS-guided prostate biopsy between March 2015 and July 2016. Systematic 12-cores prostate biopsy was performed in all patients. Of these, 100 patients were randomly assigned to two groups: compression group (n=50) underwent TRUS-guided compression on bleeding biopsy tracts immediately after prostate biopsy; non-compression group (n=50) only underwent TRUS-guided prostate biopsy. The incidence rate and duration of hematuria, hematospermia, and rectal bleeding were compared between two groups.

Results

The incidence rates of hematuria and hematospermia were not significantly different between two groups (60% vs. 64%, p=0.68; 22% vs. 30%, p=0.362, respectively, for compression vs. non-compression group). Rectal bleeding incidence was significantly lower in compression group than non-compression group (20% vs. 44%, p=0.01). However, there were not significant differences in the median duration of hematuria, hematospermia, and rectal bleeding between two groups (2, 8, and 2 days vs. 2, 10, and 1 days, p > 0.05, respectively, for compression vs. non-compression group) (Tale 1). TRUS-guided compression (p=0.004, odds ratio: OR=0.25) and patient age (p=0.013, OR= 0.93) were significant, protective factors for the occurrence of rectal bleeding after prostate biopsy in multivariable analysis (Table 2).

Conclusions

Although it has no impact on other complications, ultrasound-guided compression on bleeding biopsy tracts performed immediately after TRUS-guided prostate biopsy is a effective, practical method to treat or decrease rectal bleeding .

Funding

none

Authors
Bong Hee Park
Sung Hak Kang
Joon Se Jung
Sang Rak Bae
Yong Seok Lee
Chang Hee Han
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