Login to Access Video or Poster Abstract: MP75-09
Sources of Funding: none

Introduction

Currently, there are no guidelines defining optimal timing for definitive stone treatment in stented patients after an event of acute infection with ureteral stones and following resolution of infection. Objective: to evaluate risk factors for re-infection and re-admission in this sub-set of patients.

Methods

The records of 176 patients admitted between 2009-2016 due to ureterolithiasis and sepsis that were primarily drained with a DJ stent, were retrospectively reviewed. A comparison was carried out between 128 patients with no re-infection and 48 patients (27%) re-admitted for re-infection in the presence of a ureteral DJ stent prior to definitive stone treatment. Univariate and multivariate analysis were performed.

Results

Mean length of hospitalization due to primary septic episode was 7.4 ±5.3 days. 11.4% (20 patients) required ICU admission. Re-infection rate that required admission was 27.3% (48/176). Mean time to definite stone surgery in patients without re-infection was 72.4± 46.2 days and for those who were re-admitted with infection 42.1 ± 37.3 days._x000D_ In multivariate analysis diabetes mellitus (p=0.02) and previous endourological intervention (p=0.046) were found to be independent risk factors for re-infection. 38% of patients re-admitted for re-infection do so within 3 weeks following the primary septic episode. Mortality: one case (0.8%) during the primary septic episode and three cases (6.3%) during re-admission. _x000D_

Conclusions

Patients who suffer from diabetes or have a history of previous endourological surgery are at risk for re-infection during the period between drainage and definite stone treatment._x000D_ Re-infection episode is associated with increased risk for mortality._x000D_ Definite stone treatment within 3 weeks following primary sepsis and drainage may eliminate re-infection rate._x000D_ Optimal bacteriological and patient systemic measures at the time of definite stone treatment should be define and taken into consideration._x000D_

Funding

none