Login to Access Video or Poster Abstract: MP63-05
Sources of Funding: None

Introduction

The purpose of this study is to analyze the urodynamic features of female patients with urge urinary incontinence (UUI). The study tries to classify female UUI types according to their urodynamic features, so as to improve the level of personalized clinical diagnosis and treatment for female UUI.

Methods

A retrospective urodynamic study was performed among 102 female patients diagnosed with UUI who presented to our center between June 2015 and June 2016. All recruited patients were required to complete several examinations besides history taking, including urine analysis, ultrasound of KUB, and PVR. After that, 44 patients with urinary tract infection (UTI), cancer, stone disease, neurogenic bladder or different kinds of cystitis were excluded. The remained 58 patients were evaluated by UDS, collecting data of bladder compliance, detrusor involuntary contraction and urethra response in storage phase. The study focused on whether there were detrusor overactivity and coexsisted urethral pressures changes in storage phase.

Results

The mean age of the studied patients was 63 years (SD 10.1). All patients had normal bladder compliance in storage phase. No obvious abnormal in voiding phase were found except for 2 cases failing to induce automatic micturition. According to whether there was involuntary detrusor contraction or not in storage phase, patients were divided into two types. No involuntary detrusor contractions were demonstrated in 22 patients (37.9%), though having a strong micturition desire during UDS. Involuntary detrusor contractions were demonstrated in 36 patients?62.1%?which could be further divided into two types. Among 36 patients, simultaneous decrease of urethra pressure was demonstrated in 19 patients?32.8%?while 17 others did not(29.3%).

Conclusions

UUI often pose a negative impact on the quality of life in female patients. UDS is an excellent choice to show the pathophysiological changes of lower urinary tract in female patients with UUI. This study shows that UUI in female patients could be classified into three different types based on UDS. Type I: involuntary detrusor contractions with simultaneous decrease of urethra pressure; type II: involuntary detrusor contractions without simultaneous decrease of urethra pressure; type III: no involuntary detrusor contractions, neither simultaneous decrease of urethra pressure. These three different types of UUI shows there could be a potential difference with the underlying mechanisms, which may benefit the development of personalized treatment for UUI.

Funding

None