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OAB SCORE. A CLINICAL MODEL THAT OPTIMAZES THE PROBABILITY OF PRESENTING OVERACTIVE DETRUSOR IN URODYNIMIC STUDY

Login to Access Video or Poster Abstract: MP63-04
Sources of Funding: none

Introduction

overactive bladder (OAB) is a weakening condition that affects an important group of people, altering their quality of life. Traditionally this syndrome has been associated with the presence of involuntary detrusor contractions (IDC) in the filling phase of the cystomanometry; this urodynamic observation is called overactive detrusor (OAD). IDC identification in the urodynamic study in patients with OAB is around 50%. In this way, the association between OAB and OAD is not yet clear. Taking into account the above-mentioned information, the creation of a model that improves the predictive ability of OAB symptoms by itself is essential._x000D_ PURPOSE: to create a predictive model of IDC (OAB score) in order to improve the diagnostic accuracy of OAD, associating OAB symptoms with other clinical parameters in the female population._x000D_ _x000D_

Methods

A total of 727 women who underwent urodynamic studies for urogynecological causes were evaluated. Demographics data, personal pathological background, as well as surgical, symptoms, physical exam, mictionary record (micturition chart) and urinary culture, were collected in all patients who previously underwent uroflowmetry and urodynamic studies. A logistic regression model was carried out in order to determine independent predictors of presence of involuntary detrusor contraction (IDC). OR estimation was use to assign a score to each one of the significant variables (p<0.05) in the logistic regression model. To conclude, we performed a ROC curve in order to determine the predictive ability of the score in relation to the presence of OAD.

Results

presence of OAD was evident in 210 women (29%). In the logistic regression analysis, independent predictors of OAD were micturition urgency, UUI, nicturia, absence of SUI symptoms, presence of diabetes, reduction of vaginal trophism and vesical capacity under 150 mL. The IDC diagnosis probability increases directly as the score raises (Score 0: 4% until Score ?10: 88%). Sensitivity is 71% and specificity 72%. The area under the curve of OAB score was 0.784 (p>0.001).

Conclusions

OAB score is a clinical tool that shows higher diagnostic accuracy than OAB symptoms alone when predicting overactive detrusor (OAD).

Funding

none

Authors
Leandro Arribillaga
Ariel Montedoro
Rubén Guillermo Bengió
Marta Ledesma
Florencia Pisano
Aldana Pierantozzi
Ruben Hugo Bengió
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