Login to Access Video or Poster Abstract: MP59-11
Sources of Funding: None

Introduction

To evaluate the clinical application of computed tomography (CT)-based measurement of renal cortical volume (RCV) and split renal volume (SRV) as a single tool to assess the anatomy and renal function in patients with renal tumors before and after partial nephrectomy, and compare the findings with 99mTc-DMSA renal scan.

Methods

The data of 51 patients with a unilateral renal tumor managed by partial nephrectomy were retrospectively analyzed. The RCV of tumor-bearing and contralateral kidneys was measured using ImageJ software. Split estimated glomerular filtration rate (eGFR) and SRV calculated using this RCV were compared with the split renal function (SRF) measured with 99mTc-DMSA renal scan.

Results

A strong correlation between SRF and SRV of the tumor-bearing kidney was observed before and after surgery (r = 0.89, p < 0.001 and r = 0.94, p < 0.001). The preoperative and postoperative split eGRF of the operated kidney showed moderate correlation with SRF (r = 0.39, p = 0.004 and r = 0.49, p < 0.001). Correlation between reductions in SRF and SRV of the operated kidney (r = 0.87, p < 0.001) was stronger than that between SRF and percent reduction in split eGFR (r = 0.64, p < 0.001).

Conclusions

Compared with split eGFR, the SRV calculated using CT-based renal volumetry has a strong correlation with the SRF measured using 99mTc-DMSA renal scan. CT-based SRV measurement before and after partial nephrectomy can be used as a single modality for anatomical and functional assessment of the tumor-bearing kidney.

Funding

None