Login to Access Video or Poster Abstract: MP56-19
Sources of Funding: none

Introduction

Increasing awareness now exists of the association between RP and development of PD. Yet, little is known about how RP-associated PD (RPD) differs from de novo PD (DPD). This study was undertaken to compare patient and plaque characteristics between men with RPD and DPD.

Methods

Consecutive patients developing RPD within 2 years of their operation and patients with DPD had demographic, comorbidity, and PD characteristics recorded. All patients had an in-office curvature assessment and a penile duplex Doppler ultrasound (PDDU) following injection of an intracavernosal vasoactive agent to achieve penile rigidity. Particular attention was paid to plaque morphology as defined by an experienced sexual medicine physician. Plaque morphology was defined according to the following classification system: linear, full length, linear partial length, plate-like, septal. ‘Bilateral’ plaques (dorsal plus ventral) and calcification status (defined on ultrasound) were also recorded._x000D_ _x000D_

Results

377 men with RPD and 737 consecutive DPD patients enrolled over the same time period were studied. Mean age: RPD 64±12 vs DPD 54±16 years (p<0.01). Diabetes prevalence: 4% vs 7% (p<0.05). There were no differences in: race (87% overall Caucasian), mean early morning serum total T levels (overall 469 ng/dl), degree of curvature (38±10 degrees), direction of primary curvature (67% dorsal), presence of plate-like calcification (14%), presence of septal plaque (2%) and erectile hemodynamics (88% normal). Overt differences in plaque morphology are presented in the table.

Conclusions

Men developing PD after RP have an ethnic and comorbidity profiles similar to those of men developing PD de novo. RPD patients are more likely to have full-length linear plaques, to have concomitant dorsal and ventral plaques and less likely to have a plate-like plaque.

Funding

none