Login to Access Video or Poster Abstract: MP56-13
Sources of Funding: None

Introduction

Multiple studies have shown that Peyronie’s disease (PD) negatively impacts psychological factors including patient/partner satisfaction and overall sexual well-being. Given a relative paucity of data in this area, we sought to understand clinical factors in men who report that PD negatively impacts their sexual relationships.

Methods

We identified all men undergoing initial evaluation for PD between March 2014 and August 2016 at our institution. Patients without a current partner were excluded. During initial consultation, a detailed sexual questionnaire covering domains including erectile dysfunction, libido, ejaculatory dysfunction, and penile curvature was administered, which included a question on whether or not PD negatively impacted the current sexual relationship. Questionnaire results were subsequently compared between men based on their response to this question. Subset analysis of patients with objective curvature data was also performed. Statistical analyses including univariate and multivariate analysis was used to identify differences in those reporting negative relationship effects.

Results

242 men with PD comprised our study cohort including 146 patients (60.3%) who reported that PD had a negative impact on their sexual relationships. Median (IQR) PD duration was 18 (9;36) months and patient-estimated penile curvature was 30 (20;45) degrees. On univariate analysis, patients reporting negative relationship effects had shorter relationship durations (23 versus 27 years, p=0.04), lower IIEF-ED domain scores (14 versus 19, p=0.01), and reported higher rates of buckling (OR 2.41, p=0.003), penile shortening (OR 2.17, p=0.006), penile trauma (OR 2.38, p=0.01), and partner pain with intercourse (OR 4.12, p=0.001). On multivariate analysis, penile shortening, partner pain with intercourse, and shorter relationship duration were associated with a negative relationship effect (p?0.04). A sub-analysis of 72 men with objective curve assessment did not reveal any significant difference in negative relationship effects based on penile curvature, calcification, hourglass deformity, or stretched penile length.

Conclusions

Several patient-reported variables including penile shortening and partner pain with intercourse are associated with a higher-reported rate of negative impact on sexual relationships in patients with PD, while longer relationship durations may be protective.

Funding

None