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Prospective study comparing safety and efficacy of HoLEP for recurrent BPH after initial TURP

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Sources of Funding: none

Introduction

To prospectively evaluate safety and efficacy of Holmium laser enucleation of prostate (HoLEP) in patients with symptomatic prostate recurrence after prior transurethral resection of prostate (TURP). We also studied indication of secondary prostatectomy after prior TURP.

Methods

We prospectively evaluated 43 patients with past history of TURP who underwent HoLEP between June 2003 & May 2016 (study group). The technique of enucleation was modified based on the morphology of recurrent adenoma. 100 W holmium laser machine with 550 micron laser fiber was used. Patient’s demographics, intra and postoperative data was entered in IBM SPSS Statistics 24 software and compared with 43 randomly selected patients who underwent HoLEP without prior TURP at our institute (control group). Each control group patient was the one who underwent HoLEP immediately after the study group patient in the sequence of HoLEP patients at our institute.

Results

Patients demographics are shown in table 1. Study group patients predominantly presented with gross recurrent hematuria (58.1 %; 25/43) and had less AUA symptom score and better uroflowmetry rates than control group. The average interval between past TURP and HoLEP was 4.22 years (range- 1 month to 16 years). Table 2 & 3 reveals that the intraoperative parameters and postoperative outcome were comparable in both groups.

Conclusions

Recurrent hematuria is a commonest indication of secondary prostatectomy after primary TURP. HoLEP is a safe and effective in patients needing secondary prostatectomy after TURP and has outcome similar to those patients undergoing naïve procedure.

Funding

none

Authors
Hemendra Shah
Rashmi Shah
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