A Randomized, Controlled Trial of Active vs. Passive Voiding Trials
Sources of Funding: None
Introduction
There are national quality initiatives to prevent catheter-associated urinary tract infections (CAUTI) due to morbidity and cost. Differences between active and passive voiding trials have not been previously studied in the general hospitalized population. Active voiding trials entail filling the bladder with saline before catheter removal. Passive voiding trials involve the bladder filling with urine naturally after catheter removal. We assessed the effects of active vs passive voiding trials on time to hospital discharge and the rates of urinary tract infection (UTI) and urinary retention (UR).
Methods
In a single-center, single-blind, randomized, controlled trial, patients who had urethral catheter removal were randomized to a standardized active voiding trial or passive voiding trial. Patients undergoing urethral or bladder surgery were excluded. The outcomes of interest were the patient's time to hospital discharge after the catheter removal and the rates of UTI (defined by the National Surgical Quality Improvement Program criteria) and UR within 2 weeks of catheter removal. Logistic regression was used to identify risk factors for urinary retention.
Results
We enrolled 274 patients. Table 1 shows the differences in outcomes between active and passive voiding trials._x000D_ _x000D_ BPH (OR 5.3, p=0.007); neurological disease (OR 3.1, p=0.03); and admission to a neurosurgical ward (OR 3.6, p=0.009) were associated with increased urinary retention.
Conclusions
Patients in the active group had 64% fewer urinary tract infections than patients in the passive voiding trial group. Although patients in the active group voided nearly 3 hours sooner than patients in the passive group, there was no difference between the groups in time to hospital discharge. There was no difference in the rate of UR between the groups. BPH, neurological disease, and admission to a neurosurgical ward increased the odds of urinary retention.
Funding
None
Nathan Shaw
Helen Hougen
Hannah Agard
Robert Case
Timothy McMurry
Noah Schenkman
Tracey Krupski