Login to Access Video or Poster Abstract: MP21-10
Sources of Funding: None

Introduction

To survey long-term outcomes of dialysis patients with urothelial cancers undergone complete urinary tract exenteration (bilateral nephroureterectomy and cystectomy)

Methods

We retrospectively reviewed our patients with urinary tract urothelial cancer. A total of 42 dialysis patients who received complete urinary tract exenteration were enrolloed in our study. Seventeen patients received one-stage complete urinary tract exenteration and twenty-five patients who had multi-stage surgery. We review the demographic, clinical, surgical, and pathological data to determine what clinical and pathologic variables affected the survival between two groups.

Results

Baseline demographics were comparable in both groups. There was no significant difference in age, American Society of Anesthesiologists class, Charlson index or body mass index between the 2 groups. There were no statistically different in terms of estimated blood loss (1280 vs. 1440 ml) and total hospital stay (31 vs. 21 days). In comparsion to the multi- stage surgery, one- stage surgery was associated with a high complication rate (58.8% (10/17) vs. 8%( 2/25) ). Twenty two patients were still alive at the end of the study and 20 patients had died. The median survival after confirmation of complete urinary tract exenteration status was 27.5 months. The overall survival was not different between two groups. Charlson comorbidity index was a mandatory indicator to predict long term survival outcome.

Conclusions

In dialysis patients with urothelial cancers undergone complete urinary tract exenteration, one stage complete urinary tract exenteration had high periopearative complication rate. Charlson comorbidity index was a mandatory indicator to predict long term survival outcome.

Funding

None