Login to Access Video or Poster Abstract: MP13-15
Sources of Funding: NorthShore University Health System

Introduction

It has been demonstrated that sleep disorders (SDOs) are associated with the prevalence of nocturia in men. While previous literature supports that patients with obstructive sleep apnea (OSA), insomnia, and restless leg syndrome (RLS) are at increased risk of nocturia, the risk of daytime lower urinary tract symptoms (LUTS) in these groups has not been established. We sought to investigate the frequency of LUTS in men with and without different types of SDO.

Methods

We examined the National Health and Nutrition Examination Survey (NHANES) database between 2006-2008. Men age 18-70 years who completed the sleep questionnaires in addition to the prostate and kidney forms were included in the study. LUTS was defined as having one more of the following symptoms: hesitancy, incomplete emptying, or nocturia (>=2). Physician-diagnosed SDOs were self reported by patients. Statistical analyses were used to compare groups of men with and without a SDO.

Results

Of the 6185 men who completed all of the survey questions, 437 (7.1%) men reported a SDO. The clinical characteristics of men with and without a SDO are shown in Table 1. Men with SDOs were significantly older and significantly more likely to be Caucasian, have increased BMI and report more medical co-morbidities compared to men without SDOs. There was a significantly higher proportion of men with SDOs who reported nocturia compared to those without SDOs (39% vs 27.7%; p <.0001). Additionally, these men had a significantly higher risk of LUTS (including daytime LUTS) than men without SDOs (34.4% vs 22.8%, p <.0001). Men with OSA (31.7%) were significantly more likely to report >=2 LUTS compared to men with insomnia (18.2%) or RLS (12.5%) (p=.0002).

Conclusions

Older age, Caucasian race, elevated BMI, and increased comorbidity score appear to be associated with an increased risk of LUTS in men with SDOs. While men with SDOs report increased nocturia, they are also more likely to experience bothersome daytime LUTS. This is particularly relevant for men with OSA compared to other SDOs. Based upon the present data, clinicians should consider assessing LUTS in men with SDOs as intervention could improve both nighttime and daytime urinary symptoms.

Funding

NorthShore University Health System