Login to Access Video or Poster Abstract: MP01-14
Sources of Funding: None

Introduction

Metabolic abnormalities are associated with an increased risk for renal calculi. However, no studies to date have investigated whether metabolic factors affect the formation or recurrence of adults with bladder calculi. We aim to characterize patients with primary bladder stones, with and without kidney stones, based on their clinical factors, 24-hour urine, and stone composition.

Methods

We reviewed the medical records of patients with primary bladder stones and classified them based on their history of kidney stones, metabolic factors, clinical characteristics, and stone composition. We used descriptive statistics, multivariate analysis, and one-way ANOVA to look at associations between these parameters.

Results

Final analysis included 50 men with mean age 64 years (range: 21 to 92). 90% of these patients had a history of concurrent kidney stones. Bladder stone only formers (N=10) were older, and had greater total stone burden, higher stone recurrence rates (40% versus 25%), more metabolic abnormalities, and significantly lower urine pH (p = 0.03) compared to the concomitant kidney stone formers (N=40). Bladder stone only formers had a higher incidence of uric acid (UA) composition compared to their counterparts (62.5% versus 31.5%). Further, UA stones in the bladder demonstrated lower pH (p = 0.02) while renal UA stones were associated with lower Cit24 (p = 0.03). Stone concordance in the concomitant kidney stone group was 55.6%.

Conclusions

Primary bladder stone formers had surprisingly high rates of kidney stone formation and higher incidence of recurrence than has been previously reported. Duly, bladder stone formation may pose a risk for recurrence of bladder and/or kidney stones. The metabolic profiles of both groups, regardless of whether they made only bladder stones or both bladder and kidney stones, were similar. Aggressive treatment for outlet obstruction and metabolic abnormalities may be warranted in patients who are bladder stone only or concomitant kidney stone formers. _x000D_ _x000D_

Funding

None